Build Your System - Large Animal

Build your system – Large Animal

Swine | Canine | Primate

Please complete this form and a member of our Culex team will contact you to answer your questions, and assist in evaluating Culex-L for your needs.

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1. What is your standard study group size?

2. How are your animal catheters implanted?

Surgeries are performed in-house Surgeries are performed by a vendor

If surgeries are performed by a vendor, who is the vendor?

3. What is the average blood sample volume that you collect? The Culex® system is capable of collecting 5uL to 1.75mL, depending on the species and vial type.

Less than 500uL More than 500uL

4. For large animal species, the most common Culex® system uses an experimental cage and a swivel. However, we offer a movement responsive caging system for minipig models. The movement responsive caging makes it possible to connect multiple fluid lines and/or electrical lines directly to a single animal and greatly increases the amount of data that can be collected from each animal. Select the option below that best describes your preference.

I am working with minipigs and would like to learn more about the movement responsive caging. I will use a swivel-based system for my studies, and I already have the caging, swivel and jacket configuration that works. I will use a swivel-based system for my studies and I need help to determine the swivel, jacket and catheter combination to integrate with the Culex®.

5. Automated blood sampling is useful for a variety of applications, but it helps us when we know more about what you are trying to accomplish. Please let us know which of the below applies to you. (Select all that apply)

I am looking for an efficient way to collect PK samples. I am currently unable to collect overnight samples and would like to be able to capture that information. I need to minimize animal handling and needle stick exposure. I perform Safety Pharmacology Studies or other studies that require minimal human interaction or minimal stress to the animals. I am looking for ways to increase throughput or make my staff more efficient.

> Culex-L with Telemetry Publication

6. Taking a completely hands-off approach to running pharmacology studies can save time, reduce animal stress, and improve data accuracy. This is true for both sampling and dosing. The Empis Automated Dosing system is a software-controlled pump that integrates with the Culex® Automated Sampling system. This is most useful for infusion studies, multi-drug studies or studies that require low-stress animals.

I would like to incorporate automated infusion into my Culex® system. I will dose through an implanted catheter using a separate pump or syringe. I will dose manually using a restraint method and needle.

> Impact of dosing method to PK whitepaper

7. What route(s) of administration do you use for compound dosing? (Select all that apply)

If other, what route?

8. BASi provides training so that you can get the best start with your new equipment. For large animal models, the training is focused on the instrument. However, we may also be able to help with surgical and animal handling training.

I am interested in equipment training I would like to know if you can help me with the animal training I do not need training at this time. (You can always reach out to us if you change your mind)

9. We offer several ways to protect your equipment and protect yourself from lost time, including extended warranties, preventative maintenance visits, or a full insurance plan. Let us know if you want to learn more about any of these options.

Yes, please send me additional details. No, I do not need additional information and will simply take advantage of BASi’s Repair Services.